Emanuel Revici passed on January 9, 1998 in the first half of the 102 year of his life (by the way, his name shall be correctly uttered as [re’vɪsɪ] (stress on the 2nd syllable), not [’revɪʧɪ] or [’rɪvɪʧɪ] as many may think. There were many attempts to master his technology and principles of treatment after his death, but all of them failed — no matter what someone may claim, there is no trace of even a small success, but rather disappointments and even tragedies. Below I explain why.

Yes, there are many allusions to Revici in the Internet, — part of them is blackballing (accusations of charlatanism, fraud etc.), the other part — mindless praise based on hearsay, according to the principle “Talk the talk but not walk the walk”. Many adepts of the so-called alternative or unconventional medicine claim they have been using the ideas of Revici or even his preparations in their ways of treatment, but to be perfectly honest it’s all garbage, pathetic attempts to cover with his fame and name all sorts of nonsense like diets, the need to measure urinary pH, acidification, alkalization etc. Revici must definitely turn in the coffin every time this bullshit comes up.

Research in physiopathology as basis of guided chemotherapyI, personally, have been trying to understand and to master Revici’s technique for about 10 years. I have read his 772-page monograph of 1961 “Research in physiopathology as basis of guided chemotherapy (with special application to cancer)” far and wide 150 times (today you can find it on the web, complete or in parts), I have studied in detail all his patents and other materials associated with his name (see example on the right). Initially, I used to buy his preparations from his inheritress Elena Avram, then became self-dependent. In the beginning, experiments were conducted on myself and next-of-kin. Over the past few years the circle of “guinea pigs” has expanded — there are about 15 people today, both healthy and sick, who do voluntarily participate in further experiments. It would be arrogance and exaggeration to say that I’ve understood everything about Revici and his approach, but I do definitely understand the issue deeper and better than any other person in the world. And the most important thing about it is that I keep taking up (365 days a year) unparalleled praxis of using stuff which under threat of legal actions and losing medical licence no physician will ever dare to use.

Usually, English-speaking people get the positively colored notion of Revici and his miracle-working methodology from 2 main sources (besides internet-talk): 1) from the book by William Kelley Eidem “The doctor who cures cancer” (published 1997) and 2) by contacting the now inheritress and formerly Revici’s office manager in New York, Elena Avram. Tragically, none of them has had even a remote clue of what Revici did in reality, I mean they understand literally nothing. I must emphasize that I have no intention to insult, disclose or unmask here anyone or anything. The doctor who cures cancerYou just have to understand that anyone who’ll vigorously tell you the story of the greatness of Revici and miraculous power of his preparations is always a dabbler having no personal experience and just retelling rubbish read or heard from some other source.

No matter how possibly kind as a person, William Eidem is not a scientist, not a practitioner, not a researcher of any kind. He’s just a writer, a journalist. And like any journalist he was most interested in ballyhoo, sensation. No sensation can be made on complex things — everything should look simple, impressive and accessible, so that any housewife could get it. Well, as usually people got what they wanted: Revici’s life record in the book is set out quite well, but the methodological details... not just bad, but from bad to worse, nothing to do with reality. But tempting. No surprise it was swallowed by so many.

E. Revici & Elena AvramI don’t know how do they do now (if at all), but 4-5 years ago asking the advice and assistance by Elena Avram usually boiled down to providing you with some set of “flyers” in broken English carrying “The essence of Revici’s approach for dummies” and a list of products available for purchase. Each product had a short note like “what is it good for”, which is pure nonsense in itself. There was a time when I periodically received letters from the citizens of the USA, Israel, Germany, Ukraine (Russian emigrants, as a rule) who received “treatment” in the “Revici center” in New York (quotation marks are intentional). Overall impression has always been depressing: the representatives of the so-called “Revici center” are total ignoramuses who, among other things, barely speak English. Flyers handed out to patients for the purpose of “general education” contained an incredible amount of egregious errors replicated by mindless copy-pasting. Description of preparations was totally erroneous; “indications” in some flyers contradicted those in the others. Even the simplest questions remained unanswered.

“Quite frankly, son, out here you have exactly zero hours of experience in the field. You know nothing. In fact you know less than nothing. If you knew that you knew nothing, that would be something, but you don’t”. © Point break, 1991

It should be noted, that I do not represent any organization and do not promote anyone’s interests, but my own. Perhaps even more important is that I do not advertise or try to sell you anything here. All I currently want is to pay tribute to the deceased genius. Moreover, stuff presented here is absolutely exceptional — you won’t find something like this anywhere else, neither can anyone tell you more than I do.

So, what is important to know if you consider a possibility of treatment according to Revici? Let’s start with simpler things and then gradually proceed to more complicated issues.

  1. The most important thing to learn from the very beginning: Revici was neither charlatan nor madman possessed by some crazy idea. Revici was the real genius. He was a Romanian Jew who lived in Romania up to his 40 and, obviously, spoke Romanian only. Then he moved to France for 5 years, from where he fled to Mexico (reason: WWII) where he resided another 6 years. And only at the age of 51 he had finally moved to New York. Learning languages at that age, especially if you’re engaged in big science, is impossible — that’s obviously the reason, why Revici spoke English with strong accent and “rust”. Well, it’s exusable for a bio-chemical genius, but it’s not for the staff.

  2. One of the most popular Revici related fables is that you can eat some tuna sandwich, drink some coffee with or without cream and sugar, breathe in a paper bag and... make some judgements about the condition of your metabolism or even health in general. As any reasonable person can guess, this is total bullshit, even if someone is feeling some changes shortly afterwards — be it gallbladder colic or mood swing.

  3. Thus we logically come to another popular bullshit — the necessity to measure urinary pH and, as in the previous case, make some judgements based upon it. To urinary measurements I, personally, dedicated about 4 years. I had measured not only the proverbial pH, but almost every other parameter, namely specific gravity, surface tension, ORP (oxidation-reduction potential), chloride index etc. (see the book of Revici for details). All in all, I had tested a tank of human urine with samples from both sick and healthy people, adults and children, with and without cancer etc. And here’s what I have to tell you: routine urinary measurements are inherently useless. I mean knowing or tracing all those numbers day by day provides no valuable information, especially if a person swallows some drugs on a regular basis like candies. It’s more than enough to simply look at your urine in a glass or transparent plastic cup (this shall be a separate big topic). It’s like when anybody gets fever, you know it without thermometer. And knowing the exact value — be it 38,4 or 39,2 — is superfluous. Yes, Revici did analyze urine and tried to use it for diagnostics or, as some people used to know it, “guided therapy”. But it was just one of the initial stages of his research. Yes, of course, the urine of sick people has certain characteristic patterns or features, but exactly the same patterns from time to time occur in healthy people as well, for reasons not leading to any malady at all. I can tell you with all honesty: urinary pH is the last thing you shall pay attention to. And it has absolutely nothing to do with the pH of the blood as many used to think. So, just forget about it.

  4. The third popular legend about Revici is his miracle-work in the field of pain, heavily supported by independent clinical data provided by Dr. Welt (can be found on the web, also mentioned in the book of Revici). It’s reasonable to split the story in parts.

    Part 1. A long ago Revici introduced the notion of the so-called dualism permeating nature as a whole and human body in particular. This is to mean if there’s some balance, it’s not static or constant, but rather dynamic, i.e. due to superposition of some opposite forces acting alternately. In other words, part of the day predominates one “bunch” of forces, the other part — their antagonists. It’s like summing and averaging “ups and downs”, like a sine curve. In a long run some middle “line” (a mean value) will be obvious, around which the fluctuations occur. Obviously, besides the mean value those fluctuations will possess rhythm and sweep. Rhythm is the dependence of fluctuations of time (periodic or aperiodic); sweep is the ability to deviate from the mean. Plain and simple. For example, pH of the human urine can vary, in round figures, from 4 to 8, with 6 being the normal mean value. If this happens throughout a day, rhythm is approximately 24 hours, swing full-scale. Very few people can show such a lability. Usually, most of the time pH is either acid (<5.8) or alkaline (>6.4) accompanied by the low sweep, i.e. deviations from the mean are small, insignificant (say ±0.5) which, in turn, means absence of a good rhythm. [Important note: the term “alkaline” implies pH>7, but as the mean pH of the human urine is 6, by “alkaline” here is meant urine with pH>6. Normal person just cannot come up with urine which is actually alkaline on a regular basis.] And there’re no problems with this part of the concept.

    Part 2. The concept of general dualism had brought to light the concept of dualism in pain, which, first of all, means that some pains will intensify in the evening and night while receding during the day, and some vice versa. The dark-time pains were labeled “alkaline”, the daytime ones — “acid”. However, don’t take this correlation as a universal rule. Allegedly, the same applies to intake of foods (and drinks) — worsening after eating hints to alkaline pain, alleviation while eating — to acid; drinking sugar-containing beverages shall induce an “acid shift”. The latter actually spawned the idea to test oneself with “coffee + sugar + cream”. Respectively, if one suffers from alkaline pain, one shall be “acidified”; if there’s sign of acid pain — “alkalized”. It‘s very important to note here that the role of acidifier/alkalizer cannot be played by any substance (chosen arbitrary) that is simply acid or alkaline. This is the point missed out by all enthusiasts of that kind of “treatment”.

    Consumers of bullshit have been seriously misled by the fact that in his praxis Revici used sodium hydrocarbonate, which a) is very familiar, cheap and easy-to-get substance (baking soda); b) represents substance that is known for its use in attempts to fight cancer (e.g. look for Tulio Simoncini); c) reportedly was labeled by Albert Szentgyörgyi as “cure for all diseases”; d) is strongly alkaline, indeed. All this facts taken together turn sodium bicarbonate into sort of a dream-cure for all those who want it cheap’n’nasty. Yes, sodium bicarbonate is alkali, but it’s another quality that makes it theoretically useful – it is its ability to modify fats. The situation with acidification is slightly more complex. Firstly, Revici proved that even strong organic (or inorganic) acids do not acidify healthy tissues even in the slightest (the same applies to alkalis). Signs of acid-base changes (if any take place in response to introduction of a substance) show traumatized, cancerous, damaged and otherwise pathological tissues only. Secondly, Revici oddly did not use for the purpose of acidification (and, respectively, alkaline pain treatment) such well-known and accessible acids like acetic or citric. Moreover, there is data in his book demonstrating that acetic acid (or simply vinegars) do not acidify even pathological tissues. Further, one of the substances Revici used for acidification had alkaline pH — how do you like it?

    Part 3. It’s noteworthy that the type of pain is to be determined not by pH as such, but by a shift in urinary pH that shall take place after the exacerbation of pain. Say, if one feels like headache one shall take a leak and measure pH (put it 5,5). Then one shall do something to amplify the pain or just wait until it intensifies by itself, take another leak and measure pH again. If the second pH is greater than the first (say 5,9) the pain is assumed to be alkaline (as acidity lowers); if lower (say 5,1) — acid. Then one shall ingest an acidifier or alkalizer respectively and listen to one’s inner ear — if the pain type determination was right, the pain shall recede, if not (or something just went wrong in the meantime) — sharply intensify, sorry buddy. And that’s the point at which it falls apart. Firstly, who in one’s right mind will agree to experiment with any exacerbation of pain? Pain as a phenomenon is already bad enough to play games with it. Secondly, what if one doesn’t want to urinate or can squeeze 3 drops only? Thirdly, what if the pH won’t change?

    Part 4. I haven’t met a single person in 10 years, who would have had pains unambiguously related to the time of day. Some changes in general condition happen quite often — some feel better (in general) in the morning and during the day, the others — in the evening and at night. But pain can appear at any time and, once appeared, rarely fluctuates or recedes by itself, rather just intensifying. All attempts (and there were many) to reduce pain on the basis of its hypothetical dualism have always been less than satisfying. Yes, some change in general condition can be achieved, but no manifest pain relief. I don’t know how and with whom it worked in the praxis of Revici or Dr. Welt, but I have been unable to observe anything like this in mine. Moreover, in his book Revici explains that pain pattern can sometimes rapidly change under treatment, i.e. alkaline pain is substituted by acid one or vice versa. And go figure! Still worse is the fact that both types of pain can be present simultaneosly — treat one, exacerbate the other. Well, no objections from my side here.

    Part 5. The book of Revici of 1961 describes acid and alkaline pains only. So it was a surprise to find out in one of his patents of the 80’s that there’re pains not related to pH at all, i.e. neither acid or alkaline. Now that’s wow... For treatment of such pains Revici proposed substance which is not just toxic, but highly toxic — exposure to it can result in pulmonary edema, severe allergic reactions, dermatitis, skin necrosis, acute kidney damage (see toxicity issue below). When handling it, it is recommended to put on rubber gloves, rubber apron and, preferably, gas mask. According to the patent the stuff is to be injected into painful area or swallowed. In diluted form, of course, but... doesn’t your anus consrict already? The respective flyers of Elena Avram mentioned only one “side-effect” of that stuff — “mild increase in heart rate and blood pressure”. As you can see, it’s definitely not the worst to expect. I, personally, sniffed that stuff (undiluted) without gas mask, and I can tell you straight: the body reacted in a very frightening way. But let’s take into account that I have been suffering from allergies since infancy, so maybe I’m just overly sensitive. The same substance is also mentioned in the book of 1961, but without any connection to pain — then Revici used it to treat cancer. Later it somehow found application in treatment of asthma, allergies and rheumatoid arthritis...

    Part 6. In short, up to date (the beginning of 2017) I’m not aware of any way to ensure efficient and warranted pain relief other than using opium derivatives. Unfortunately, opium is also one-way ticket, which one would hardly happy with. Yes, of course, there’s lot of analgesics like ibuprofen, baralgin, diclofenac, aspirin etc. But they’re all such poisons that I don’t really know what is better — to suffer from pain or swallow that stuff. In this regard, it’ll be interesting to know that even a small injection of morphine (or some other opium derivative) prevents hematological shock, i.e. self-digestion of blood in response to injury or invasion of a noxious agent. No other drug used in traditional medicine possesses the same ability.

    Basically, the main human drama is once the body begins fighting something “tooth and nail” (i.e. literally to death) it usually meets death — remember this simple truth. One of the basic forms of attack is blowing up its own leycocytes (white blood cells) whereby all their toxic content being spilled into the blood — this is called hematological shock, hemo-shock or hemoclasia. Hemo-shock can be prevented or even suppressed by opium alkaloids. Yes, one can do it on a regular basis and feel relatively well, but the pathology will also develop quickly (e.g. cancer) and every other time hemo-shock will become potentially more and more lethal. That’s why many cancer patients end up on incremental doses of morphine finally witnessing the decline of its efficacy even in mega-doses.

  5. Thus, we’ve come to toxicity issue. Toxicity is the ability of a substance to cause death or serious damage to health, i.e. it’s the characteristic of a substance as such, on one hand. On the other, toxicity is strongly relative — what’s extremely toxic to some, is almost completely non-toxic to others. For example, one can drink 3 bottles of bourbon and get away, while for the other a single glass is enough to achieve sort of acute poisoning. In June 2010, the (in)famous rock-star Ozzy Osbourne donated his body to the Natural History Museum of London with request to investigate his body after death to find out how the hell could he consume hellish mixtures of drugs and alcohol 40 years in a row and stay alive. The man is 68 years old now, he made ca. 50 attempts to quit drugging and drinking, underwent 12 detox/rehab programs, but returned to his habits 2 months of abstinence at latest. Well, bad habits die hard. Very often binges continued days or weeks without a break. Many times Ozzy ordered cocaine in milk packs, poured it out into a large bowl and sniffed it falling face-down. Or take, say, painters (especially in the third world), who hang out indoors for days painting walls and ceilings with paints and dyes reeking beyond imagination. Or those daily working with paint-and-lacquer materials (e.g. at car service) or drawing roadmarkings with extremely toxic enamels. And have no complaints in doing so. Additionally, many of them are heavy smokers. And for some a couple slices of orange or a piece of fish is already toxic enough! So let’s say it again: toxicity is a relative term.

    According to Wikipedia, almost all substances used by Revici are toxic, highly toxic and some even carcinogenic. Ain’t funny pun: treat cancer with carcinogens. Well, no surprise, actually. Fight fire with fire. Usually, those substances find application in perfume and mining industries, in manufacture of plastics and epoxy resins, rubber vulcanization, ship impregnation etc. I don’t mean to scare anyone — it’s just the fact to be better aware of. In other words, for a normal healthy person with sensitive nervous system (which is almost synonym to “not suppressed immune system”) all those substances can be very dangerous. I don’t know, why the therapy of Revici is being tagged “non-toxic”. Non-toxic for whom? For a heavy smoking painter? Well, it definitely is. But not in general. I, personally, feel Revici preparations seeping-reeking even through the plugs of glass vials. One-two drops of many of them was enough for me to understand, that it’s not my cup of tea or will ever be. They literally make my blood boil. On the other hand, I used to know many people with cancer, who shot themselves with those preparations many times with no adverse effects. Here’s one of those substances — the oily solution of ethyl mercaptan. If you want to turn gray — just check that shit out. There’s a mentioning in the book of Revici that ecopolice (or Greenpeace) asked him to stop using this substance because of the stench spreading for kilometers off the laboratory. Some time ago I got this thing in two vials — one was used by a woman with cervical cancer, the other I had taken to the forest and buried to hell. Out of sight, out of mind.

    Actually, one never knows what to expect after the intake of Revici stuff. Sometimes everything’s just fine, but the other time one can get elephant-like legs, stroke, anaphylactic shock or blackening and falling off of a testicle. And I’m not joking. But now you can understand, why there’s no trace of success by his so-called successors. You can also imagine, how powerful some diseases are (e.g. cancer or rheumatoid arthritis) that the only way to defeat them is to use really frightening substances. But, again, there are people who can swallow Revici preparations easily and feel little discomfort after, let alone serious consequences. But those people do not constitute the majority.

  6. Accordingly, the next obvious question to shed some light upon: when the preparations of Revici are contraindicated, shall be used with great caution and/or in micro-dosages? Since virtually all Revici preparations directly affect the “friend or foe” relationships within a body (i.e. immunity in a variety of its forms and stages), they are very dangerous to people who are allergic or subjected to some inadequate reactions to certain stimuli (food, drugs, insects, etc.). Thanks to Revici preparations I, personally, experienced anaphylactic shock 4 times. Further, strong reactions can be expected from people with general hypersensitivity (to scents, paints, exhaust gases, impurities, etc.). Drastic deterioration may occur in people with autoimmune diseases. It seems like Revici was able to treat autoimmune diseases, but, as I understand it, inappropriate choice of preparations can be sort of irreversible. It is very dangerous to give Revici preparations to people having severely damaged organs, tissues, implants, transplants or long story of swallowing medications. Otherwise one can regret one was born. Well, actually, many regret already — they’re just unaware that it can be much worse.

    So, who’s left? People with reduced sensitivity to toxic substances in general, not irritated by polluted environment, which is reflected in their almost non-excitable nervous system, which, in turn, equals to inactive or sluggish immunity. Those are (but not limited to) painters, metal-workers, gas-fitters, workers of printing houses, garages, factories, plants and other hazardous industries, unskilled workers, servicemen, all those ladies (and sometimes men) dousing themselves with perfumes to such an extent that a gas mask grade A is necessary to enter porch or elevator after them, preferably heavy smokers, alcoholics and so on. In short, the first candidates to Revici treatment are people who are perfectly tolerable to petrochemicals, aromatic hydrocarbons and impurities in general. It’s exactly them, who “suddenly” get diagnosed with 4th stage inoperable cancer, just like “out of the blue”. A person with normal active immunity cannot work or live in a hazardous environment, and those who can are there precisely because of their sluggish immune system.

  7. Within the frame of dualistic concept Revici introduced two global characteristics for the opposing forces — anabolic and catabolic. Respectively, anything promoting the action of the former (or resisting the action of the latter) — this way or another — is to be considered anabolic. If vice versa — catabolic. It can be substances, temperature, time of the day, sunbathing, some other external stimuli or even food. Naturally, food-issue immediately attracted to Revici many nutrition-obsessed blockheads — lists of “acidifying” and “alkalizing” foods appeared, as well as the advices of health-check by means of tuna sandwich, cup of coffee with sugar and milk etc. Revici did widely use the notions “anabolic” and “catabolic” both in his book of 1961 and in his later patents and in public appearances. It goes without saying that the book by William Kelley Eidem “The doctor who cures cancer” is literally stuffed with those words too. Thus it’s not surprising that Philistines adopted them readily. But while Revici understood what he was talking about, the Philistines just understood that it sounded good. By the way, the proverbial “acid pains” Revici correlated with anabolic action while “alkaline pains” — with catabolic, though both acids and alkali as such have almost nothing to do with it. What’s there in reality and why is the correlation exactly like that is discussed below.

    The term “anabolic” characterizes chemical processes in which simple substances combine to form more complicated ones, i.e. those processes are clearly constructive. To put it another way: they counteract entropy. And entropy (in simple words) is a measure of disintegration, chaos. For example, both wound healing and tumor growing is anabolic.

    The term “catabolic”, on the contrary, characterizes processes in which complex substances degrade to simpler ones, i.e. those processes are clearly destructive and increase entropy. For example, oxidation of a substance followed by liberation of energy (heat in particular) is catabolic. As is, say, assimilation of glucose with the help of insulin.

    However, I recommend not “to think in those terms” as well as not to use them in conversations about Revici related stuff — they’re seriously misleading. The heart of the matter is as follows: by “anabolic” Revici meant processes with the participation of fatty acids with low number of double bonds (mono-unsaturated, saturated) or substances/impacts lowering the number and activity of double bonds. Respectively, by “catabolic” Revici meant processes with the participation of fatty acids with high number of double bonds (polyunsaturated or PUFAs) or substances/impacts increasing the number and activity of double bonds. For example, turning a non-conjugated PUFA into a conjugated one with subsequent radical change of its properties and biological activity which is characteristic e.g. for irradiation or severe trauma. And this is exactly why PUFAs, double bonds in molecules of which are in a specific conjugated disposition are especially interesting. And especially dangerous too.

  8. I promised in the very beginning that the deeper we go, the harder they come. And the more interesting it gets. Come up to a window (or mirror) and touch it firmly with your forehead, cheek or palm — what do you see? Fatty mark(s). Well, you don’t even have to go “that far” — look at your eternally fat-smeared phone. No matter how carefully you wash yourself and degrease your body, the fat is back up very soon. Our bodies are literally soaked with fats and oils. And fats-oils have a tendency to become rancid, i.e. they change their properties (to be exact — deteriorate) when exposed to air or better to say oxygen.

    Everybody knows the specific unpleasant smell of an old body. Aside from the smell of medications and excrements the bodies of the aged smell of… rancid fats! Deep research in the field of rancidity of fats allowed Revici to systemize the oxidation processes occurring in vivo. In order to understand the matter we must take a moderately deep dive into some details. Take a look at some fatty acids widely used in food and perfume industries.

    Palmitic acid — saturated fatty acid with 16 carbons (i.e. with no double bonds in the molecule at all), the main constituent of the palm oil.
    Palmitic acid

    Oleic acid — mono-unsaturated fatty acid with 18 carbons (i.e. with a single double bond).
    Oleic acid

    Linoleic acid — unsaturated fatty acid with 17 carbons and 2 non-conjugated double bonds (i.e. separated by more than one single bond), one of the most abundant fatty acids in nature and the main constituent (60%) of the extremely popular sunflower oil. Belongs to pro-inflammatory FA Omega-6.
    Linoleic acid
    Linoleic acid

    However, the very same linoleic acid can have double bonds in conjugated position (i.e. separated by just one single bond) — in this case it turns from usual linoleic acid into conjugated linoleic acid (CLA). Take a special note: the number and types of atoms constituting the molecule are absolutely the same! Just their interconnections are slightly different.
    Conjugated linoleic acid

    Linolenic acid — unsaturated fatty acid with 18 carbons and 3 non-conjugated double bonds, the second most common FA constituting almost 60% of the flax seed oil. Occurs in two modifications — alpha & gamma.
    Альфа-линолевая кислота
    Гамма-линолевая кислота

    Again: the number and types of atoms in the molecule of both α-linolenic (also known as ALA) and γ-linolenic (also known as GLA) acids are perfectly the same. The only difference between the two molecules is the disposition of double bonds — the last double bond in α-linolenic acid is located 3 carbons off the end of the chain, while in γ-linolenic it’s 6 carbons off. And that’s exactly the reason why the first is Omega-3 and the second — Omega-6. As is known, FAs ω-3 are anti-inflammatory, while ω-6 — pro-inflammatory. And the only difference is the dislocation of double bonds!

    Arachidonic (eicosatetraenic) acid — unsaturated fatty acid with 20 carbons and 4 non-conjugated double bonds (standing for “-tetra-” in the name), which constitutes about 25% of the adrenal reserve. Belongs to pro-inflammatory FA ω-6. It’s abundant in the brain, liver and milk fat of mammals — it’s exactly that very acid to be blamed for many forms of headaches (though not exclusively of course). Until recently medical science had absolutely no clue as to why is that acid present in the body at all. Revici solved this puzzle as far back as in the 40’s! Our bodies extract this FA either from food (manly seafood or dairy products) or synthesize from linoleic acid.
    Arachidonic acid

    Oxidation of arachidonic acid results in appearance of especially powerful “hard-to-handle” derivatives — eicosanoids, which cause wide spectrum of pathological body reactions such as inflammation, allergy, fever, spasms, wild immune reactions, termination of pregnancy; they directly influence pain sensitivity, blood pressure, cellular division etc. One of the most “cruel” eicosanoids are leukotrienes, which, in particular, cause bronchospasm underlying the famous incurable condition known as asthma. Leukotrienes are also the cause of the headaches resistant to usual analgesics. Their characteristic feature is 3 conjugated double bonds — that’s why they were labeled conjugated trienes. Similar substances appear in a body following irradiation, streptococcus-staphylococcus infection etc.
    Leukotriene
    Leukotriene LTB4

    Eicosapentaenic (timnodonic) acid (EPA) — unsaturated fatty acid with 20 carbons and 5 non-conjugated double bonds (standing for “-penta-” in the name). Belongs to anti-inflammatory FA ω-3. Together with docosahexaenic acid (for which it can serve as precursor) constitutes an integral part of many popular food additives. In nature it’s abundant in salmon, cod, sardines. This is that very acid so many hopes were pinned upon in the treatment and prevention of cardiovascular diseases, cancer etc. But, unfortunately, those hopes just cracked up — brief improvement is always followed by progressive aggravation. Though it’s clear that the hype of “incredible benefits” of those acids is virtually eternal.
    Eicosapentaenic acid

    Docosahexaenic (cervonic) acid (DHA) — unsaturated fatty acid with 22 carbons and 6 non-conjugated double bonds (standing for “-hexa-” in the name). It’s an important constituent of the brain, skin, sperm, retina etc. which makes it sort of “very neurologic” acid. Otherwise see EPA above.
    Docosahexaenic acid

    I have always been wondering how one can expect to treat hard, odd, unconventional conditions with accessible easy-to-get from food substances — it’s just naïve. So I’m not surprised that all attempts like this are basically useless. At least, it shall be clear that both usual PUFAs and unsaturated FAs do not have a real therapeutic value. Well, extreme conditions demand extreme responses.

    For example, the substance which is able to really effectively neutralize the most powerful carcinogens like methylcholanthrene, benzopyrene, benzanthracene etc. is parinaric acid — unsaturated fatty acid with 18 carbons and 4 conjugated double bonds. This acid is derived from the seeds of Makita tree growing on Fiji or from Impatiens balsamina growing in Bangladesh and Burma.
    Parinaric acid

    By the way, the reference to Impatiens balsamina contains pretty interesting details on the use of that plant in local medicine. For example, the juice from leaves is used in treatment of warts and snakebites, flowers — in treatment of burns etc. And extract from the seeds appeared to be deadly to antibiotic-resistant strains of Helicobacter. And it’s not a coincidence as you can guess. Conjugates! Do you get it?

    Unlike single bond, double bond significantly increases the ability of carbons “sitting” on it, to bind oxygen. There’re few options of fatty acids oxidation briefly explained below. Option 1 is when molecular oxygen (O2) joins the carbon “sitting” on a double bond which results in appearance of hydroperoxide (...=C—O—O—H). As this combination is reversible, the fatty acid releases it back, usually as free radical. The process of turning of molecular oxygen into free radical is absolutely physiological (normal) and is called “activation” of oxygen. If there’re problems with activation — the body is in trouble.

    Most naturally occurring PUFAs (especially those available commercially) are characterized by the presence of 2 or 3 non-conjugated double bonds. And this fact is very important, as the carbon located between 2 double bonds becomes especially active (e.g. see the 11th carbon in the molecule of  linoleic acid). Philistines don’t have to sink into the depths of physical chemistry — it’s enough to know that that very carbon located between 2 double bonds possesses a very special ability to bind oxygen. And that’s exactly the reason why some fatty acids are labeled “essential” (or conditionally-essential). The paradox is that human body is able to use them (for health-maintenance) but is unable to synthesize. This is why it’s considered that such fatty acids must be ingested with respective foods.

    Oxidation of such PUFAs under normal conditions by temperatures below +50°С both in vitro and in vivo is followed by the appearance of harmful (even useful) hydroperoxides (—O—O—H). However, increasing temperature leads to a radically different combination resulting in appearance of epoxides (if anion O22− is fixed) and peroxides (if O—O is fixed). In short, there’re 3 types of rancidity:

    1. Hydrolytic rancidity — it’s when fats split into free fatty acids and glycerol (to be exact — glycerides) under attack of lipolytic (i.e. fat-destroying) enzymes which come from a) molds; b) microbes; c) represent plain lipase that’s always present in tissues rich in fats. The main feature of this type of rancidity is the appearance of free FAs.

    2. Rancidity affecting just saturated fatty acids (those having no double bonds at all). It is due to the so-called Knoop β–oxidation which results in appearance of methyl-ketones with 7, 9 or 11 carbons and characteristic odor. The process is usually performed by peroxidases present in some molds. The main feature of this type of rancidity is that it degrades saturated FAs with low number of carbons (8-12) only.

    3. Rancidity affecting double bonds. Under normal conditions, only conjugated fatty acids oxidize with the formation of peroxides, while non-conjugated FAs (like oleic, linoleic, linolenic) produce hydroperoxides. However, in the course of research it became evident that oxidation of non-conjugated FAs with several double bonds even under normal conditions can lead to such a dislocation of double bonds that their conjugated isomers appear!

    Let’s utter it one more time: some enzymes in vivo can influence the oxidation of usual normal PUFAs (resulting in rancidity) in such a way that those PUFAs, which normally just activate oxygen and oxidize producing useful hydroperoxides, now produce abnormal peroxides which can be even observed in urine. For example, this happens after irradiation, streptococcal infection, ingestion of selenium-based preparations or fatty acids with high number of double bonds (over 4).

  9. As mentioned above (see anabolic/catabolic issue) the proverbial acid pains Revici considered anabolic, while alkaline ones — catabolic. But it remained unclear, why is the correlation exactly like this.

    Tissues rich in fats not allowing effective fixation of oxygen (and respectively its activation) more or less extract energy from anaerobic glycolysis, which leads to appearance of acidic substances, mainly lactic acid. As difficulties with oxygen fixation result from reduced activity of double bonds (e.g. due to lack of PUFAs) the pain is anabolic. By the way, don’t stuff yourself with olive oil (which is considered very useful) — its main constituent is oleic acid (55-85%). It’s not bad, but not a reason to consume it in excess either. The whole Italy, for example, consumes this oil in excess lifelong, but the situation with cancer there is depressive. On the other hand, in Thailand, where nearly all foods are prepared with considerably “less useful” sesame oil, in which oleic and linoleic fatty acids are present 50/50, and everybody consumes seafood soaked with allergenic PUFAs all-the-year-round, the cancer situation is one of the better on the whole planet.

    Tissues where fixation of oxygen results in appearance of peroxides (not normal hydroperoxides; btw “hydro-” stems from hydrogen) gradually lose the ability to use hydrogen which, in turn, results in pH-increase. As abnormal fixation of oxygen is due to increased activity of double bonds (e.g. due to presence of conjugated FAs) the pain is catabolic.

    Now think carefully: how the hell stuffing sick person with acids (say, vinegar or something) or alkalis can influence the fixation of oxygen in any way? No way! As to alkalis, to find a really alkaline food one has to try very hard — there’s almost nothing naturally alkaline in Nature, except boiled water. This means if you take any raw vegetable (or drink like whole fresh milk), squeeze juice from it and measure its pH you’ll never find values above 6.9 — everything is more or less acid. And fruit juices are not just acid but extremely acid. Distlilled water is also acid. Sending greetings to blockheads. Substances Revici used in such cases won’t acidify or alkalize anything — they influence the fixation of oxygen.

  10. Iceberg I’m often asked: what is Revici method all about in few words? What constitutes its essence? What do his preparations do in a body, why, how, by which means etc. Here’s the answer in one sentence:

    The method of Revici is the Art of shifting double bonds in organic molecules and regulating oxygen fixation on a substrate.

    Sounds pretty simple, but in reality — just like on the picture.

    Introduction into a body of almost any of Revici preparations causes some shift in great number of double bonds, mainly in fats. The word “some” is intentionally underlined as no one knows, where and how do they shift exactly. It’s only clear that they do shift bringing about fundamental structural changes in the flesh without changing its molecular composition. And structural changes are obviously followed by changes in properties and modus operandi. Bright example: if you want to radically change the properties and biological activity of some fatty acid — to turn it from pro-inflammatory into anti-inflammatory — you “just” have to shift all double bonds 3 carbons closer to the end of its molecule. And you’re there. A little bit more complicated example: absolutely inactive in its anti-carcinogenic properties fatty acid can become active (at least slightly) if its double bonds get conjugated. Still more complicated example: cold (directly or indirectly) causes such a shift of double bonds in some fatty acids that some end up with sore (inflamed) throat, the others enjoy facial herpes never seen there before. Respectively, those in whom double bonds for some reason don’t make inflammatory shifts are not subjected to common cold or something like this. Moreover, ingestion of some special conjugated fatty acids can make body almost completely refractory to many viruses! And this is not in theory — Revici had proved it decades ago, I have been proving it in my own praxis.

    Dislocation of double bonds can occur under many circumstances, one of which is emotional breakdown or simply mental shock. In general, any physical or mental overload is possible due to the energy of double bonds — extreme powersurges demand extreme forms of oxygen fixation. Other factors influencing double bonds shifts are temperature, sunbathing, irradiation, consumption of drugs, alcohol, tobacco, coffee, some foods etc. Similar but still more powerful influence show viruses, microbes, bacteria and other germs. The mobility (or “pliancy”, i.e. tendency to shift) of double bonds shows clear seasonal influence as well as dependence on time of the day — at some periods they shift readily, sometimes reluctantly (if at all). This explains many seasonal disorders and swings in overall condition often felt by sick people throughout a day.

    Of great importance is sex. It’s not without purpose that women are considered fair sex and men — sterner sex. As well as it’s not incidentally that life expectancy of women is greater than that of men, and when choosing life companion women consciously or unconsciously (instinctively) look for the one who can offer better welfare or better protection. This is because females are genetically much less equipped for production and use of protective fatty acids than males. And this is one of the reasons why females respond to treatment not as good as males (in general). For man it’s difficult to begin — ’cos he’s rough and tough, boys don’t cry etc. Women usually don’t need special invitation to treatment — they like to be treated, do it lifelong and easily treat others, especially children, in their blind and often stupid caring rage. By the way, children are subjected to illnesses much more than adults for the very same reason — lack of proper fatty acids. And the virus spreading from a child is much more virulent than the same virus spreading from an adult. It’s quite plausible that “obligatory” childhood diseases literally teach young body build up proper defense. Yes, feeding sick person with antibiotics often solves the problem, but the body remains untaught, vulnerable and prone to further infections.

    The system of informational exchange and signaling within a body is essentially based on lipoids (fatty acids or fat-like substances). The defense system keeping track of and responding to noxious interventions, i.e. immunity, is predominantly lipoidic too. And this is why changing properties of lipoids affects nearly all vital functions. This is, among other things, that very reason why ingestion of oily preparations of Revici has usually far-reaching, ambivalent, often unpredictable consequences/implications.
    Before After
    Shifting double bonds or bringing about some other changes in lipoids with the help of Revici preparations can, indeed, lead to (auto)resorption of massive tumors. But it can also result in violent immune reactions, especially autoimmune (some of them known as cytokine storm or anaphylactic shock). I had a patient with cancer of sigmoid who took 2 Revici preparations — it didn’t influence his cancer, but did blacken his testicles, whereafter they fell off and he died. And there’re a lot of cases like this, not necessary of such severity, but nevertheless. Yes, Revici preparations display powerful and undoubted influence on a body, but you never know beforehand how it will end. Especially taking into account that modern people are literally soaked with poisons — say hello to food, drug, perfume and other industries.

    Revici pharmacopeiaThat’s why Revici preparations are pretty hard to investigate — it’s very risky to administer them to people suffering from, say, allergies, asthma, rheumatoid arthritis, glomerulonephritis, streptococcal-staphylococcal infections, cirrhosis, hepatitis etc. meaning situations when general condition of a person is shaky, weak, constantly balancing on the brink of some attack, or some organ is alreay damaged to a degree it’s about to die off. In such cases you have to know for sure that it will help, otherwise consequences can be irreversible. But how can you know? (see below)

    The other big stumbling block in the way is that, as a rule, introduction into a body of many theoretically effective (from therapeutic point of view) oils is counteracted by the adrenals. As adrenals is that very organ directly influencing activity and conformation of double bonds. To some extent the situation is similar to liver which is able to more or less neutralize many drugs ingested by a human being. In other words, a normal liver strongly opposes all those chemicals doctors feed to sick person. This is to mean that if there would be no liver, every swallowed pill would work as a whole, but as long as liver is present, it leaves from a pill just some part. This is the reason why Revici tried to develop oily preparations which would not be appreciably neutralized by the adrenals, on one hand, and influenced pathology on the other, which makes his preparations even more dangerous — in case of mistake their elimination or cancellation of their action is very problematic, they stay in a body and keep going just like Energizer-rabbit.

    Still worse is that adrenals do have direct vertical axis to brain. Therefore, in people prone to allergies or simply sensitive, the smell of Revici preparations alone seeping through vial plugs can make one’s blood boil or even result in panic attack. And if swallowed, even 1-2 drops... it can be catastrophe. But I must emphasize it once again: there’re many people who can swallow Revici preparations in high dosages (40cc, 60cc, 100cc etc.) and have no complaints whatsoever. It depends on hormonal content of the adrenals, chemical composition of a body and body mass. It’s interesting to note that a person with powerful but stressed adrenals reacts to appearance in the body of conjugated fatty acids with pulling-aching sensation in the lumbar region. Sometimes it’s so intense that one feels like arching of the loins. Naturally, many begin immediately suspect something wrong with the kidneys or spine, but it’s neither — it’s adrenals “feeling” the threat of looming double bonds shift and building up the defense. Sometimes unpleasant sensations arise in the occipital region (or the head just begins to ache) and joints. It’s not surprising that when one gets flu, one often feels like the whole body is aching (head included) and joints twisting. People whose bodies (adrenals in particular) are well equipped to counteract conjugates, frequently describe their condition as “feel like about to get sick, but nothing happens”.

    For a layman the notion of a “double bond” between atoms is almost incomprehensible. But one can proceed this way: buy 2 identical bottles of a vegetable oil and properly irradiate one of them. Then open up both bottles and take a spoon from each... Feel the difference!

Addendum:
Revici’s pharmacopeia, A-Z
(chemical heritage of Revici, i.e. list of substances he used in his late activities)

Necessary explanations:

Four main points to keep in mind now and forever:

  1. The essence of Revici’s approach in cancer is to evoke targeted autoimmune aggression or apoptosis. To achieve this goal, special substances are introduced into a body, which have a propensity to bind specifically to cancerous cells changing their properties so that they become targets for immune attack or commit suicide.
  2. The essence of Revici’s approach in autoimmune diseases (e.g. rheumatoid arthritis) is the mirror-image of the one in cancer. Quenching of autoimmune aggression is achieved by introduction of substances which bind to cells under attack and change their properties so that the immune system stops “seeing" them giving them a rest.
  3. Curiously enough, it’s not uncommon that one and the same substance can serve both purposes. That’s why the essence of Revici’s approach in other diseases/disorders is one or the other or a mix of two.
  4. The biggest stumbling block in the way — you never know which targets will be hit, if any. You can have all preparations of Revici and still have no success. Most often you get something like this: substances you administer a) are not bound to cancerous cells of that particular cancer, accordingly they don’t draw attention of immune system neither do they commit suicide, so the cancer remains unaffected; b) just exacerbate existing autoimmune condition; c) don’t affect what’s desired, but make some additional changes in a body leading to new problems, wild symtoms etc. Obviously, Revici possessed some exceptional flair in this area multiplied by the great experience (70 years, 365 days a year) and possibility to look around at the cellular level with the help of very expensive equipment (AAS). All other attempts of treatment “according to Revici” (even with his original preparations) are always just shots in the dark. For example, how do you know whether a patient needs lipidic copper, calcium, potassium, zinc or some other element? With rare exceptions, there’s no way to “sense” it — the only way to know it for sure is to AAS-investigate a sample of abnormal tissue. It’s not accidentally that Revici used about 35 different preparations, not just 5. After administration of Revici stuff by guesswork you never know, whether it’s the beginning of rapidly approaching end or some temporary crisis you just have to endure. Sometimes it’s fuckin’ scary, sometimes consequences are simply irreversible.

Column Product:

  • “Oil” underneath product name means the product represents exactly what it means — viscous oil that can be
    • essentially clear (“c”)
    • with a trace of precipitate (“p”) or
    • markedly muddy (“m”), especially if shaken.
  • “Sol” — there are also some oily products representing mixtures of various oils with special solvents making product more liquid.
  • “Dry” — powdered incapsulated stuff.
  • “Wat” — water solution. Not every water solution is prepared just by simple dilution of a substance in water — sometimes additional heating is required. According to Revici, water solutions are inherently inferior to oily substances, except perhaps very strong caustic acids.

As to colors, substances can be

  • almost colorless (“t”)
  • some shade of yellowish-brown (“y”)
  • orange-red (“r”)
  • dark green (“g”) or
  • black to the extent it’s almost opaque (“b”).

That’s why where there’s “b” in the description, it always stands alone. Similarly, where there’s “wat”, there’s no need in “t”, as water solutions discussed here are always colorless. It’s necessary to note, that although I know the nature of most substances (constituents, method of preparation, dilution etc.) I cannot work it out in detail here.

Column Acronym & Purport, on one hand, contains my assumption regarding the origin of the product name, which is pretty useful. In fact, if there’re no exact data, knowing what hides behind the acronym can give valuable information on what it can be or which action it’s intended to have.

“Incorporated” means element (copper, calcium, potassium etc.) “built-in” into oil, which is achieved by prolonged boiling of selected vegetable oil in the presence of proper salt of an element — in some cases oils turn completely clear, otherwise become muddy. Why incorporate something into oil and not use just salt of an element like they do it in dietary supplements? Listen here. On the other hand, any reasonable person would want to know, what does this or that substance do in the body. Wouldn’t you?

I must emphasize it once again: a diagnosis or condition as such (say, BPH) is not a ground at all to feed a patient with any of incorporated elements (say, zinc in 302-package). The only solid ground to administer oil with an element inside is proving (by means of AAS) that its concentration within the pathological tissue (say, prostate) is much lower than it shall be (in a healthy person).

It is important to know that Revici did widely use substances with hapten- or epitope-esque properties (but didn’t use any of these notions). To put it simply: there exist some relatively simple substances which, when introduced into a body, gravitate towards some “dormant” intact proteins turning them into objects of immune attack, i.e. those substances possess strong allergenic properties. Or they change the molecular structure of some fats (not proteins) so that they also turn allergenic. Most of the substances are taken orally, some can be both taken orally and injected, a few suppose intramuscular route only. Tip: if single dosage of a substance is supposed to be few drops only or the percentage of dilution (in water or oil) is very low (<1%), you can be pretty sure you deal with powerful hapten/epitope. And that’s exactly why Revici’s preparations can be very dangerous (see Contraindications below). If the target of wild allergic reaction is tumor — it’s probably OK, but what if it’s something else? Perhaps, the biggest problem with Revici preparations is not their toxicity or allergenicity as such, but it’s that you never know the consequences. It’s very likely they will kill not just tumor, but something else as well (say, some nerve or part of the brain). Especially if a person has been intensively pre-treated/medicated, i.e. poisoned with conventional methods.

Another interesting observation: if you take a close look at all the variety of medications used for treatment of inflammations, you notice that regardless of their chemical structure they all have one common property — the ability to shrink proteins. This ability is more or less pronounced by the following elements (their salts or other compounds): Al, Bi, Ca, Cl, Cu, I, Zn, as well as by some tanning agents, acids, alcohols etc. And presence of a shrinking agent helps tissues resist swelling and disentegration.

One of the cornerstones of Revici’s approach is that his therapeutic lipids bypass normal tissues — they gravitate towards pathological tissues only, get absorbed by them, whereafter the incorporated elements are allegedly liberated. This selective attraction is due to the fact that pathological tissues are always rich in very specific lipids while normal tissues are not. Principle “same to same” in work. As to inflammatory processes, there’s a problem to expect: yes, some incorporated elements he used are anti-inflammatory indeed, but their carriers (overheated oils) being inherently allergenic simply cannot be anti-inflammatory, they’re “neutral” at best, but rather pro-inflammatory.

Columns Indications: Information stemming directly from original papers of Revici (the book of 1961, patents of the 80’s etc.) or his public appearances can be considered trustworthy. Information derived from any other source (mainly from Elena Avram & Co.) is totally unreliable. It’s noteworthy that most indications of Elena Avram have almost nothing in common with those of Revici himself. They’re even idiotic here and there (see e.g. REA). Where the hell has she been drawing them from, is beyond my imagination. By the way, there are exactly 25 patents of Revici and only 3 by Elena Avram published after his death in 2002 (you can find all of them below). Numbers in [] reflect the order of historical appearance of the patents.

Column Contraindications: Curiously enough, Revici almost never mentioned any, so I had to derive them from my own 10-years praxis by notorious trial-and-error or better to say step-on-rake approach. Well, the real meaning of contraindications is rather “apply with extreme care” than “better don’t use at all”, i.e. it’s a warning of danger. In order not to mention it every time, I must emphasize it once and for all:

Most preparations of Revici (if not all) can be very dangerous to people suffering from allergies, headaches (which is just a usual constituent of allergy), autoimmune diseases or adrenal deficiency.

Can ≠ are, but forewarned = armed. Being allergic since early childhood myself and knowing people with various autoimmune conditions, who experienced sharp aggravation after intake of any of Revici’s preparations, I can swear it. That’s why seeing “allergy” in some indications has always made me to perceive it as a jeer. It’s quite possible that some forms of allergy respond well to that kind of treament, but definitely not all. I can also admit, that the deliverance from allergy may imply passing through some crisis or temporary aggravation, but getting over the condition rapidly rolling downhill without knowing how long you shall endure it, is usually impossible. Still worse, Revici’s substances are especially dangerous to people with “punctured” hematoencephalic barrier — in this case they will immediately hit the brain with unpredictable consequences, although in his speech Revici claims they cannot pass through. In fact they can and will, otherwise he wouldn’t be able to treat cancers of the brain, would he? As one of the consequences, those subjected to frequent headaches can easily experience aggravation by tenfold. ND = No Data for the time being, which usually means unsufficient experience with a substance to make a meaningful conclusion.

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